Which medication is associated with suicidal thoughts as a potential adverse effect?

Roflumilast is a medication that functions as a phosphodiesterase-4 (PDE4) inhibitor and is primarily used for the management of chronic obstructive pulmonary disease (COPD). One of the significant considerations when prescribing Roflumilast is its potential to lead to psychiatric side effects, including suicidal thoughts and behaviors. This association is highlighted in various clinical studies and product labeling, indicating that healthcare providers should carefully monitor patients for any signs of mood changes or suicidal ideation while on this medication.

Understanding the adverse effects of medications is crucial for safe prescribing practices, especially regarding those that may impact mental health. While other medications listed also have their respective side effects, Roflumilast stands out due to its specific linkage to the increased risk of suicidal thoughts, making it particularly important to educate patients about these risks and the necessity of reporting any concerning symptoms.