Which side effect should be monitored during montelukast therapy?

Montelukast, a leukotriene receptor antagonist, is often prescribed for the management of asthma and allergic rhinitis. One of the notable side effects associated with this medication is the potential for changes in mood or behavior. This can manifest as increased irritability, agitation, or even more severe mood changes, including suicidal thoughts in rare cases.

Monitoring for mood changes during montelukast therapy is crucial, especially in pediatric populations where these effects might be more pronounced. The changes in mood or behavior may not be immediately apparent and can vary in severity, making it essential for healthcare providers, patients, and caregivers to be vigilant.

In contrast, while some patients might experience skin rashes or other side effects, mood changes are specifically noted in clinical data surrounding montelukast use and thus warrant closer attention. Healthy appetite variations, such as increases or decreases, and frequent urination do not have strong correlations with montelukast therapy and are not prioritized monitoring parameters for this medication.